Many investigations on the spermicidal effects of various chemical agents have been reported.
Holzaepfel and Greenlee studied the spermicidal activities of various organic substances by the method of Brown and Gamble but the anther conducted a study on the lowest spermicidal ccncentration of twelve water soluble chemical agents available in Korea.
The semen used in this series was obtained from healthy Korans rainging from 20 to 25 years of age. Each semen was collected in a clean and dried Petri dish. I
In order to minimize individual differences, 5 semen samples were mixed together and then used
within 3 hours at room temperature.
Each drop of semen and candidate solution were dropped respectively on the silde glass 2nd mixed homogenously.
Under a microscope the complete cessation of the sperm. motility in the solution which occurred wit hin 3 minutes indicates the lowest concentration of the candidate solution.
The results obtained are as follows:
1) The lowest spermicidal concentrations of NaOH, HCI, HgCl2, Tartaric acid, Acetic acid, Hydrogen Peroxide are within a range of 0.5% to 0.8%.
2) The lowest spermicidal concentration of powdered soap, Tide (U.S. made) is 4%.
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